Medicine

Notes on Thrombotic Microangiopathy

Background Recently, I was presenting approach to Thrombotic Microangiopathy in hospital. I made the following notes, which I feel will be beneficial for the residents. Introduction TMA are of diverse etiologies but have unified manifestation a. MAHA (Coombs negative, increased LDH, schistocytes) b. Thrombocytopenia c. Organ injury (ischemic) TMA has unified pathogenesis a. Endothelial dysfunction b. Microinfarcts Approach to treatment a. Primary TMA syndromes (ADAMTS deficiency, HUS): treatment to be of the cause

Jugular Venous Waveforms and Carotid Pulsations in Tachyarrhythmia Diagnosis

Background The content of this post was written by me few years ago. It builds conceptual framework on JVP and carotid wave analysis for tachyarrhythmia diagnosis. Many concepts written in this post are practical with a bit of practice and spending time with patients. The techniques written here can be used as important adjunct to 12 lead surface ECG tracing in diagnosing tachyarrythmia. Introduction Tachyarrhythmia diagnosis is a challenge that all of us face as daily routine.